6-chloro-5-fluoro-1H-indole-2-carboxylic acid methyl ester
6-Chloro-5-fluoro-1H-indole-2-carboxylic acid ethyl ester
CAS: 169674-00-4
Molecular Formula: C11H9ClFNO2
6-chloro-5-fluoro-1H-indole-2-carboxylic acid methyl ester - Names and Identifiers
6-chloro-5-fluoro-1H-indole-2-carboxylic acid methyl ester - Physico-chemical Properties
| Molecular Formula | C11H9ClFNO2 |
| Molar Mass | 241.65 |
| Density | 1.401 |
| Boling Point | 380.6°C at 760 mmHg |
| Flash Point | 184°C |
| Vapor Presure | 5.39E-06mmHg at 25°C |
| Storage Condition | Room Temprature |
| Refractive Index | 1.61 |
6-chloro-5-fluoro-1H-indole-2-carboxylic acid methyl ester - Introduction
acid ethyl ester, also known as (ATE) methyl acetate, is an organic compound. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: acid ethyl ester is a solid crystal, which can be a white to light yellow solid.
-Melting point: about 65-68 ° C.
-Solubility: Soluble in many organic solvents, such as ethanol, dimethyl sulfoxide and chloroform.
Use:
acid ethyl ester has important applications in the field of medicine:
-Drug intermediate: It can be used as an intermediate for the synthesis of various drugs, especially the synthesis of biologically active compounds.
-Anticancer drug research: This compound is used to study new anti-tumor and anti-cancer drugs.
Method:
acid ethyl ester is usually prepared by organic synthesis methods. A common preparation method is as follows:
1. 6-Chloro-5-fluoro-1H-indole-2-carbaldehyde and acetic acid are reacted under acidic conditions, (6-Chloro-5-fluoro-1h-indole-2-carboxylic acid) acetate was produced.
2. React the product with alcohol to obtain acid ethyl ester.
Safety Information:
-No acute toxicity is apparent under normal conditions of use.
-But as an organic compound, it may cause certain harm to the human body, such as irritation and allergic reactions.
-Wear appropriate protective equipment, such as gloves and eye protection, and maintain good ventilation during operation.
-Properly store, use and dispose of the compound in accordance with the chemical's safety data sheet and operational safety measures.
Nature:
-Appearance: acid ethyl ester is a solid crystal, which can be a white to light yellow solid.
-Melting point: about 65-68 ° C.
-Solubility: Soluble in many organic solvents, such as ethanol, dimethyl sulfoxide and chloroform.
Use:
acid ethyl ester has important applications in the field of medicine:
-Drug intermediate: It can be used as an intermediate for the synthesis of various drugs, especially the synthesis of biologically active compounds.
-Anticancer drug research: This compound is used to study new anti-tumor and anti-cancer drugs.
Method:
acid ethyl ester is usually prepared by organic synthesis methods. A common preparation method is as follows:
1. 6-Chloro-5-fluoro-1H-indole-2-carbaldehyde and acetic acid are reacted under acidic conditions, (6-Chloro-5-fluoro-1h-indole-2-carboxylic acid) acetate was produced.
2. React the product with alcohol to obtain acid ethyl ester.
Safety Information:
-No acute toxicity is apparent under normal conditions of use.
-But as an organic compound, it may cause certain harm to the human body, such as irritation and allergic reactions.
-Wear appropriate protective equipment, such as gloves and eye protection, and maintain good ventilation during operation.
-Properly store, use and dispose of the compound in accordance with the chemical's safety data sheet and operational safety measures.
Last Update：2024-04-09 02:00:43
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